Complement receptor 1 (CR1, CD35) association with susceptibility to leprosy

BACKGROUND: Pathophysiological mechanisms are still incompletely understood for leprosy, an urgent public health issue in Brazil. Complement receptor 1 (CR1) binds complement fragments C3b/C4b deposited on mycobacteria, mediating its entrance in macrophages. We investigated CR1 polymorphisms, gene e...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Kretzschmar, Gabriela Canalli, Oliveira, Luana Caroline, Nisihara, Renato Mitsunori, Velavan, Thirumalaisamy P., Stinghen, Sérvio Túlio, Stahlke, Ewalda R. S., Petzl-Erler, Maria Luiza, de Messias-Reason, Iara José T., Boldt, Angelica Beate Winter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103516/
https://ncbi.nlm.nih.gov/pubmed/30092084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006705
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