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Protein motion in the nucleus: from anomalous diffusion to weak interactions

Understanding how transcription factors (TFs) regulate mammalian gene expression in space and time is a central topic in biology. To activate a gene, a TF has first to diffuse in the available space of the nucleus until it reaches a target DNA sequence or protein (target site). This eventually resul...

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Detalhes bibliográficos
Publicado no:Biochem Soc Trans
Main Authors: Woringer, Maxime, Darzacq, Xavier
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103463/
https://ncbi.nlm.nih.gov/pubmed/30065106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20170310
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