Effects of tolvaptan on renal function in chronic kidney disease patients with volume overload

BACKGROUND: Fluid overload in chronic kidney disease (CKD) is generally controlled by diuretics, with potentially harmful effects on renal function. The efficacy of tolvaptan, a vasopressin V2-receptor antagonist and aquaretic, has not been evaluated for fluid control in CKD with reduced renal funct...

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Bibliographic Details
Published in:Int J Nephrol Renovasc Dis
Main Authors: Suzuki, Shunji, Hanafusa, Norio, Kubota, Kenji, Tsuchiya, Ken, Nitta, Kosaku
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2018
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103308/
https://ncbi.nlm.nih.gov/pubmed/30147354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJNRD.S167694
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