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A red-emissive antibody–AIEgen conjugate for turn-on and wash-free imaging of specific cancer cells

An antibody–AIEgen conjugate is designed and developed as a “turn-on” fluorescent probe for wash-free specific cancer cell imaging. The cetuximab-conjugated AIEgen shows red fluorescence only when it is internalized and accumulated in cancer cells with overexpressed epidermal growth factor receptor...

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Publicado en:Chem Sci
Main Authors: Shi, Xiujuan, Yu, Chris Y. Y., Su, Huifang, Kwok, Ryan T. K., Jiang, Meijuan, He, Zikai, Lam, Jacky W. Y., Tang, Ben Zhong
Formato: Artigo
Idioma:Inglês
Publicado: Royal Society of Chemistry 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103257/
https://ncbi.nlm.nih.gov/pubmed/30155197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc01054k
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