Rscreenorm: normalization of CRISPR and siRNA screen data for more reproducible hit selection

BACKGROUND: Reproducibility of hits from independent CRISPR or siRNA screens is poor. This is partly due to data normalization primarily addressing technical variability within independent screens, and not the technical differences between them. RESULTS: We present “rscreenorm”, a method that standa...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:BMC Bioinformatics
Egile Nagusiak: Bachas, Costa, Hodzic, Jasmina, van der Mijn, Johannes C., Stoepker, Chantal, Verheul, Henk M. W., Wolthuis, Rob M. F., Felley-Bosco, Emanuela, van Wieringen, Wessel N., van Beusechem, Victor W., Brakenhoff, Ruud H., de Menezes, Renée X.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2018
Gaiak:
Methodology Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102854/
https://ncbi.nlm.nih.gov/pubmed/30126372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2306-z
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