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Clustering of circular consensus sequences: accurate error correction and assembly of single molecule real-time reads from multiplexed amplicon libraries

BACKGROUND: Targeted resequencing with high-throughput sequencing (HTS) platforms can be used to efficiently interrogate the genomes of large numbers of individuals. A critical issue for research and applications using HTS data, especially from long-read platforms, is error in base calling arising f...

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Publicado en:BMC Bioinformatics
Autores principales: Francis, Felix, Dumas, Michael D., Davis, Scott B., Wisser, Randall J.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102811/
https://ncbi.nlm.nih.gov/pubmed/30126356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2293-0
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