MET-overexpressing myxofibrosarcoma frequently exhibit polysomy of chromosome 7 but not MET amplification, especially in high-grade cases: clinical and pathological review of 30 myxofibrosarcoma cases

BACKGROUND: Myxofibrosarcoma (MFS) is one of the most common soft tissue sarcomas. Previous studies have shown that MET protein overexpressed in MFS patients and can serve as a prognostic factor. The reasons for MET protein overexpression include amplification of the MET gene, which is located on ch...

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Detalhes bibliográficos
Publicado no:Diagn Pathol
Main Authors: Ma, Shirong, Fan, Linni, Liu, Yixiong, Wang, Yingmei, Yu, Kangjie, Wang, Lifeng, Fang, Na, Liu, Fang, Guo, Shuangping, Wang, Zhe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102798/
https://ncbi.nlm.nih.gov/pubmed/30126419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-018-0733-9
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