Quercetin-3-O-β-D-glucoside decreases the bioavailability of cyclosporin A through regulation of drug metabolizing enzymes, transporters and nuclear receptors in rats

Quercetin is a flavonoid compound that is widely present in food and drink. Quercetin-3-O-β-D-glucoside (Q3GA) is a major metabolite of quercetin. The aim of the present study was to investigate the effect of Q3GA on the pharmacokinetics of orally and intravenously administered cyclosporin A (CsA) i...

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Publicado en:Mol Med Rep
Main Authors: Yang, Tingyu, Liu, Yani, Huang, Xixi, Zhang, Rui, Yang, Chunxiao, Zhou, Jiali, Zhang, Yu, Wan, Jing, Shi, Shaojun
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102747/
https://ncbi.nlm.nih.gov/pubmed/30015887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.9249
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