SH2B1 protects against OGD/R-induced apoptosis in PC12 cells via activation of the JAK2/STAT3 signaling pathway

Apoptosis acts as the primary pathogenesis of cerebral ischemia/reperfusion (I/R) injury. Prior studies have revealed the effects of src homology 2 (SH2)B adaptor protein 1 (SH2B1) in myocardial infarction; however, involvement of SH2B1 in cerebral I/R injury and the underlying mechanisms remain to...

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Foilsithe in:Mol Med Rep
Main Authors: Yuan, Jiang, Zeng, Lei, Sun, Yanpeng, Wang, Na, Sun, Qiang, Cheng, Zhaohui, Wang, Yunfu
Formáid: Artigo
Teanga:Inglês
Foilsithe: D.A. Spandidos 2018
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Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102733/
https://ncbi.nlm.nih.gov/pubmed/30015896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.9265
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