To ERV Is Human: A Phenotype-Wide Scan Linking Polymorphic Human Endogenous Retrovirus-K Insertions to Complex Phenotypes

Approximately 8% of the human genome is comprised of endogenous retroviral insertions (ERVs) originating from historic retroviral integration into germ cells. The function of ERVs as regulators of gene expression is well established. Less well studied are insertional polymorphisms of ERVs and their...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Wallace, Amelia D., Wendt, George A., Barcellos, Lisa F., de Smith, Adam J., Walsh, Kyle M., Metayer, Catherine, Costello, Joseph F., Wiemels, Joseph L., Francis, Stephen S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102640/
https://ncbi.nlm.nih.gov/pubmed/30154825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00298
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