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Synthesis and Evaluation of C15 Triene Urushiol Derivatives as Potential Anticancer Agents and HDAC2 Inhibitor

A series of C15 triene urushiol derivatives were synthesized and evaluated for their anti-HepG2 aggregation in vitro. The results indicated that all compounds had an effective anti-HepG2 vitality. Compound 1 was a potent inhibitor of HepG2 with IC(50) of 7.886 μM and 150 μM against LO2. Moreover, co...

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Bibliografski detalji
Izdano u:Molecules
Glavni autori: Qi, Zhiwen, Wang, Chengzhang, Jiang, Jianxin
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102549/
https://ncbi.nlm.nih.gov/pubmed/29751548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23051074
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