Physiological and Pathological Brain Activation in the Anesthetized Rat Produces Hemodynamic-Dependent Cortical Temperature Increases That Can Confound the BOLD fMRI Signal

Anesthetized rodent models are ubiquitous in pre-clinical neuroimaging studies. However, because the associated cerebral morphology and experimental methodology results in a profound negative brain-core temperature differential, cerebral temperature changes during functional activation are likely to...

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Vydáno v:Front Neurosci
Hlavní autoři: Harris, Samuel S., Boorman, Luke W., Das, Devashish, Kennerley, Aneurin J., Sharp, Paul S., Martin, Chris, Redgrave, Peter, Schwartz, Theodore H., Berwick, Jason
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102348/
https://ncbi.nlm.nih.gov/pubmed/30154690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00550
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