Intrathecal delivery of human ESC-derived mesenchymal stem cell spheres promotes recovery of a primate multiple sclerosis model

Nonhuman primate experimental autoimmune encephalomyelitis (EAE) is a valuable model for multiple sclerosis, an inflammatory demyelinating disease in the central nervous system (CNS). Human embryonic stem cell-derived mesenchymal stem cells (EMSC) are effective in treating murine EAE. Yet, it remain...

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Bibliographic Details
Published in:Cell Death Discov
Main Authors: Yan, Li, Jiang, Bin, Niu, Yuyu, Wang, Hongxuan, Li, Enqin, Yan, Yaping, Sun, Huiyan, Duan, Yanchao, Chang, Shaohui, Chen, Guokai, Ji, Weizhi, Xu, Ren-He, Si, Wei
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102276/
https://ncbi.nlm.nih.gov/pubmed/30131877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-018-0091-0
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