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O-GlcNAcylation reduces proximal tubule protein reabsorption and promotes proteinuria in spontaneously hypertensive rats

Hypertensive individuals are at greater risk for developing chronic kidney disease (CKD). Reducing proteinuria has been suggested as a possible therapeutic approach to treat CKD. However, the mechanisms underlying the development of proteinuria in hypertensive conditions are incompletely understood....

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Foilsithe in:J Biol Chem
Main Authors: Silva-Aguiar, Rodrigo Pacheco, Bezerra, Nathália C. F., Lucena, Miguel C., Sirtoli, Gabriela M., Sudo, Roberto T., Zapata-Sudo, Gisele, Takiya, Christina M., Pinheiro, Ana Acacia S., Dias, Wagner Barbosa, Caruso-Neves, Celso
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102134/
https://ncbi.nlm.nih.gov/pubmed/29954945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001746
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