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Bioprintable Alginate/Gelatin Hydrogel 3D In Vitro Model Systems Induce Cell Spheroid Formation

The cellular, biochemical, and biophysical heterogeneity of the native tumor microenvironment is not recapitulated by growing immortalized cancer cell lines using conventional two-dimensional (2D) cell culture. These challenges can be overcome by using bioprinting techniques to build heterogeneous t...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Jiang, Tao, Munguia-Lopez, Jose, Flores-Torres, Salvador, Grant, Joel, Vijayakumar, Sanahan, De Leon-Rodriguez, Antonio, Kinsella, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102030/
https://ncbi.nlm.nih.gov/pubmed/30010644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57826
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