Bioprintable Alginate/Gelatin Hydrogel 3D In Vitro Model Systems Induce Cell Spheroid Formation

The cellular, biochemical, and biophysical heterogeneity of the native tumor microenvironment is not recapitulated by growing immortalized cancer cell lines using conventional two-dimensional (2D) cell culture. These challenges can be overcome by using bioprinting techniques to build heterogeneous t...

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Bibliographische Detailangaben
Veröffentlicht in:J Vis Exp
Hauptverfasser: Jiang, Tao, Munguia-Lopez, Jose, Flores-Torres, Salvador, Grant, Joel, Vijayakumar, Sanahan, De Leon-Rodriguez, Antonio, Kinsella, Joseph M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MyJove Corporation 2018
Schlagworte:
Bioengineering
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102030/
https://ncbi.nlm.nih.gov/pubmed/30010644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57826
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