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Protocol for MicroRNA Transfer into Adult Bone Marrow-derived Hematopoietic Stem Cells to Enable Cell Engineering Combined with Magnetic Targeting

While CD133(+) hematopoietic stem cells (SCs) have been proven to provide high potential in the field of regenerative medicine, their low retention rates after injection into injured tissues as well as the observed massive cell death rates lead to very restricted therapeutic effects. To overcome the...

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Bibliographic Details
Published in:J Vis Exp
Main Authors: Hausburg, Frauke, Müller, Paula, Voronina, Natalia, Steinhoff, Gustav, David, Robert
Format: Artigo
Language:Inglês
Published: MyJove Corporation 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101762/
https://ncbi.nlm.nih.gov/pubmed/29985305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57474
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