Chemical Reversion of Conventional Human Pluripotent Stem Cells to a Naïve-like State with Improved Multilineage Differentiation Potency

Naïve human pluripotent stem cells (N-hPSC) with improved functionality may have a wide impact in regenerative medicine. The goal of this protocol is to efficiently revert lineage-primed, conventional human pluripotent stem cells (hPSC) maintained on either feeder-free or feeder-dependent conditions...

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Vydáno v:J Vis Exp
Hlavní autoři: Park, Tea Soon, Zimmerlin, Ludovic, Evans-Moses, Rebecca, Zambidis, Elias T.
Médium: Artigo
Jazyk:Inglês
Vydáno: MyJove Corporation 2018
Témata:
Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101693/
https://ncbi.nlm.nih.gov/pubmed/29939183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57921
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