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FM Dye Cycling at the Synapse: Comparing High Potassium Depolarization, Electrical and Channelrhodopsin Stimulation

FM dyes are used to study the synaptic vesicle (SV) cycle. These amphipathic probes have a hydrophilic head and hydrophobic tail, making them water-soluble with the ability to reversibly enter and exit membrane lipid bilayers. These styryl dyes are relatively non-fluorescent in aqueous medium, but i...

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Publicado en:J Vis Exp
Autores principales: Kopke, Danielle L., Broadie, Kendal
Formato: Artigo
Lenguaje:Inglês
Publicado: MyJove Corporation 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101380/
https://ncbi.nlm.nih.gov/pubmed/29889207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57765
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