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Prevention of apoptotic onset rescues from glomerular tubular disconnection and podocyte loss in proteinuric kidney disease

There is a great need for treatment that arrests progression of chronic kidney disease. Increased albumin in primary urine leads to apoptosis and fibrosis of podocytes and tubular cells and is a major cause of functional deterioration. There have been many attempts to target fibrosis but few to targ...

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Detalhes bibliográficos
Publicado no:Kidney Int
Main Authors: Burlaka, Ievgeniia, Nilsson, Linnéa M, Scott, Lena, Holtbäck, Ulla, Eklöf, Ann-Christine, Fogo, Agnes B, Brismar, Hjalmar, Aperia, Anita
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101029/
https://ncbi.nlm.nih.gov/pubmed/27217195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.03.026
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