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A 3D-QSAR Study on the Antitrypanosomal and Cytotoxic Activities of Steroid Alkaloids by Comparative Molecular Field Analysis

As part of our research for new leads against human African trypanosomiasis (HAT), we report on a 3D-QSAR study for antitrypanosomal activity and cytotoxicity of aminosteroid-type alkaloids recently isolated from the African medicinal plant Holarrhena africana A. DC. (Apocynaceae), some of which are...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Nnadi, Charles Okeke, Althaus, Julia Barbara, Nwodo, Ngozi Justina, Schmidt, Thomas Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6100617/
https://ncbi.nlm.nih.gov/pubmed/29738470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23051113
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