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Targeting GLI Transcription Factors in Cancer
Aberrant activation of hedgehog (Hh) signaling has been observed in a wide variety of tumors and accounts for more than 25% of human cancer deaths. Inhibitors targeting the Hh signal transducer Smoothened (SMO) are widely used and display a good initial efficacy in patients suffering from basal cell...
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| Pubblicato in: | Molecules |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6100584/ https://ncbi.nlm.nih.gov/pubmed/29695137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23051003 |
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