Simultaneous Determination and Pharmacokinetics of Peimine and Peiminine in Beagle Dog Plasma by UPLC-MS/MS after the Oral Administration of Fritillariae ussuriensis Maxim and Fritillariae thunbergii Miq Powder

A simple and high sensitive ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method was developed and validated for the simultaneous determination of peimine and peiminine in beagle dog plasma after the oral administration of Fritillariae ussuriensis Maxim and Friti...

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Veröffentlicht in:Molecules
Hauptverfasser: Wang, Zhibin, Cao, Feng, Chen, Yajun, Tang, Zhenqiu, Wang, Zhenyue
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6100562/
https://ncbi.nlm.nih.gov/pubmed/29958456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23071573
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