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Strategies for Enhancing the Permeation of CNS-Active Drugs through the Blood-Brain Barrier: A Review

Background: The blood brain barrier (BBB) is a dynamic and functional structure which poses a vast challenge in the development of drugs acting on the central nervous system (CNS). While most substances are denied BBB crossing, selective penetration of substances mainly occurs through diffusion, car...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Zeiadeh, Isra’, Najjar, Anas, Karaman, Rafik
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6100436/
https://ncbi.nlm.nih.gov/pubmed/29843371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23061289
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