Design and Synthesis of Lactams Derived from Mucochloric and Mucobromic Acids as Pseudomonas aeruginosa Quorum Sensing Inhibitors

Bacterial infections, particularly hospital-acquired infections caused by Pseudomonas aeruginosa, have become a global threat with a high mortality rate. Gram-negative bacteria including P. aeruginosa employ N-acyl homoserine lactones (AHLs) as chemical signals to regulate the expression of pathogen...

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Publicado en:Molecules
Main Authors: Almohaywi, Basmah, Taunk, Aditi, Wenholz, Daniel S., Nizalapur, Shashidhar, Biswas, Nripendra N., Ho, Kitty K. K., Rice, Scott A., Iskander, George, Black, David StC., Griffith, Renate, Kumar, Naresh
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6100351/
https://ncbi.nlm.nih.gov/pubmed/29735954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23051106
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