Polyamidoamine Dendrimers for Enhanced Solubility of Small Molecules and Other Desirable Properties for Site Specific Delivery: Insights from Experimental and Computational Studies

Clinical applications of many small molecules are limited due to poor solubility and lack of controlled release besides lack of other desirable properties. Experimental and computational studies have reported on the therapeutic potential of polyamidoamine (PAMAM) dendrimers as solubility enhancers i...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Molecules
Main Authors: Shadrack, Daniel M., Swai, Hulda S., Munissi, Joan J. E., Mubofu, Egid B., Nyandoro, Stephen S.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6100328/
https://ncbi.nlm.nih.gov/pubmed/29895742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23061419
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