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Understanding the Role of Anti-PEG Antibodies in the Complement Activation by Doxil in Vitro

Infusion reactions (IRs) are common immune-mediated side effects in patients treated with a variety of drug products, including, but not limited to, nanotechnology formulations. The mechanism of IRs is not fully understood. One of the best studied mechanisms of IRs to nanomedicines is the complement...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Neun, Barry W., Barenholz, Yechezkel, Szebeni, Janos, Dobrovolskaia, Marina A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6100003/
https://ncbi.nlm.nih.gov/pubmed/30002298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23071700
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