p53-inducible DPYSL4 associates with mitochondrial supercomplexes and regulates energy metabolism in adipocytes and cancer cells

The tumor suppressor p53 regulates multiple cellular functions, including energy metabolism. Metabolic deregulation is implicated in the pathogenesis of some cancers and in metabolic disorders and may result from the inactivation of p53 functions. Using RNA sequencing and ChIP sequencing of cancer c...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Nagano, Hidekazu, Hashimoto, Naoko, Nakayama, Akitoshi, Suzuki, Sawako, Miyabayashi, Yui, Yamato, Azusa, Higuchi, Seiichiro, Fujimoto, Masanori, Sakuma, Ikki, Beppu, Minako, Yokoyama, Masataka, Suzuki, Yutaka, Sugano, Sumio, Ikeda, Kazuhiro, Tatsuno, Ichiro, Manabe, Ichiro, Yokote, Koutaro, Inoue, Satoshi, Tanaka, Tomoaki
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099896/
https://ncbi.nlm.nih.gov/pubmed/30061407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804243115
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