Mitochondria-Targeting Small Molecules Effectively Prevent Cardiotoxicity Induced by Doxorubicin

Doxorubicin (Dox) is a chemotherapeutic agent widely used for the treatment of numerous cancers. However, the clinical use of Dox is limited by its unwanted cardiotoxicity. Mitochondrial dysfunction has been associated with Dox-induced cardiotoxicity. To mitigate Dox-related cardiotoxicity, consider...

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Publicat a:Molecules
Autors principals: Shi, Wei, Deng, Hongkuan, Zhang, Jianyong, Zhang, Ying, Zhang, Xiufang, Cui, Guozhen
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099719/
https://ncbi.nlm.nih.gov/pubmed/29921817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23061486
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