(−)-Epigallocatechin 3-Gallate Synthetic Analogues Inhibit Fatty Acid Synthase and Show Anticancer Activity in Triple Negative Breast Cancer

(−)-Epigallocatechin 3-gallate (EGCG) is a natural polyphenol from green tea with reported anticancer activity and capacity to inhibit the lipogenic enzyme fatty acid synthase (FASN), which is overexpressed in several human carcinomas. To improve the pharmacological profile of EGCG, we previously de...

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Gepubliceerd in:Molecules
Hoofdauteurs: Crous-Masó, Joan, Palomeras, Sònia, Relat, Joana, Camó, Cristina, Martínez-Garza, Úrsula, Planas, Marta, Feliu, Lidia, Puig, Teresa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099607/
https://ncbi.nlm.nih.gov/pubmed/29751678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23051160
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