(−)-Epigallocatechin 3-Gallate Synthetic Analogues Inhibit Fatty Acid Synthase and Show Anticancer Activity in Triple Negative Breast Cancer

(−)-Epigallocatechin 3-gallate (EGCG) is a natural polyphenol from green tea with reported anticancer activity and capacity to inhibit the lipogenic enzyme fatty acid synthase (FASN), which is overexpressed in several human carcinomas. To improve the pharmacological profile of EGCG, we previously de...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Crous-Masó, Joan, Palomeras, Sònia, Relat, Joana, Camó, Cristina, Martínez-Garza, Úrsula, Planas, Marta, Feliu, Lidia, Puig, Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099607/
https://ncbi.nlm.nih.gov/pubmed/29751678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23051160
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