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Carbazole Derivatives’ Binding to c-KIT G-Quadruplex DNA

The binding affinities of three carbazole derivatives to the intramolecular G-quadruplex (GQ) DNA formed by the sequence 5′-AGGGAGGGCGCTGGGAGGAGGG-3′, derived from the c-KIT 1 oncogene region, were investigated. All carbazole cationic ligands that differed in the substituents on the nitrogen atom we...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Głuszyńska, Agata, Juskowiak, Bernard, Kuta-Siejkowska, Martyna, Hoffmann, Marcin, Haider, Shozeb
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099540/
https://ncbi.nlm.nih.gov/pubmed/29747481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23051134
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