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Synthesis, Immunosuppressive Properties, and Mechanism of Action of a New Isoxazole Derivative

This work describes the synthesis of a new series of isoxazole derivatives, their immunosuppressive properties, and the mechanism of action of a representative compound. A new series of N′-substituted derivatives of 5-amino-N,3-dimethyl-1,2-oxazole-4-carbohydrazide (MM1–MM10) was synthesized in reac...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Mączyński, Marcin, Borska, Sylwia, Mieszała, Katarzyna, Kocięba, Maja, Zaczyńska, Ewa, Kochanowska, Iwona, Zimecki, Michał
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099534/
https://ncbi.nlm.nih.gov/pubmed/29949951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23071545
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