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Non‐enzymatic cross‐linking of collagen type II fibrils is tuned via osmolality switch
An important aspect in cartilage ageing is accumulation of advanced glycation end products (AGEs) after exposure to sugars. Advanced glycation results in cross‐links formation between the collagen fibrils in articular cartilage, hampering their flexibility and making cartilage more brittle. In the c...
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| Publicado no: | J Orthop Res |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6099510/ https://ncbi.nlm.nih.gov/pubmed/29334127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.23857 |
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