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Non‐enzymatic cross‐linking of collagen type II fibrils is tuned via osmolality switch

An important aspect in cartilage ageing is accumulation of advanced glycation end products (AGEs) after exposure to sugars. Advanced glycation results in cross‐links formation between the collagen fibrils in articular cartilage, hampering their flexibility and making cartilage more brittle. In the c...

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Détails bibliographiques
Publié dans:J Orthop Res
Auteurs principaux: Pouran, Behdad, Moshtagh, Parisa R., Arbabi, Vahid, Snabel, Jessica, Stoop, Reinout, Ruberti, Jeffrey, Malda, Jos, Zadpoor, Amir A., Weinans, Harrie
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099510/
https://ncbi.nlm.nih.gov/pubmed/29334127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.23857
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