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Synthesis of Both Enantiomers of Chiral Phenylalanine Derivatives Catalyzed by Cinchona Alkaloid Quaternary Ammonium Salts as Asymmetric Phase Transfer Catalysts

A practical synthesis of both enantiomers of unnatural phenylalanine derivatives by using two pseudoenantiomeric phase transfer catalysts is described. Through asymmetric α-alkylation of glycine Schiff base with substituted benzyl bromides and 1-(bromomethyl)naphthalene under the catalysis of O-ally...

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Detalles Bibliográficos
Publicado en:Molecules
Main Authors: Jin, Lei, Zhao, Shuai, Chen, Xin
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099405/
https://ncbi.nlm.nih.gov/pubmed/29895754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23061421
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