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Antibody repertoire analysis in polygenic autoimmune diseases

High‐throughput sequencing of the DNA/RNA encoding antibody heavy‐ and light‐chains is rapidly transforming the field of adaptive immunity. It can address key questions, including: (i) how the B‐cell repertoire differs in health and disease; and (ii) if it does differ, the point(s) in B‐cell develop...

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Pubblicato in:Immunology
Autori principali: Bashford‐Rogers, Rachael J. M., Smith, Kenneth G. C., Thomas, David C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099162/
https://ncbi.nlm.nih.gov/pubmed/29574826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12927
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