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Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs

BACKGROUND: The search for an optimal experimental model in pharmacology is recently focused on (mini)pigs as they seem not only to be an alternative source of cells and tissues for xenotherapy but also an alternative species for studies on drug metabolism in man due to similarities between (mini) p...

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Bibliografiske detaljer
Main Authors: Soucek, Pavel, Zuber, Roman, Anzenbacherová, Eva, Anzenbacher, Pavel, Guengerich, F Peter
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC60991/
https://ncbi.nlm.nih.gov/pubmed/11737866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-1-11
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