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Growth Inhibition of a Novel Iron Chelator, DpdtC, against Hepatoma Carcinoma Cell Lines Partly Attributed to Ferritinophagy-Mediated Lysosomal ROS Generation

Some iron chelators display significant anticancer activity that may involve ferritin degradation either in proteasomes or in lysosomes, and the latter might involve ferritinophagy with a period. However, the correlation of ferritinophagy with anticancer activity of iron chelator was not fully deter...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Huang, Tengfei, Sun, Yanjie, Li, Yongli, Wang, Tingting, Fu, Yun, Li, Cuiping, Li, Changzheng
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6098875/
https://ncbi.nlm.nih.gov/pubmed/30154950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4928703
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