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Cross-species evidence from human and rat brain transcriptome for growth factor signaling pathway dysregulation in major depression

An enhanced understanding of the pathophysiology of depression would facilitate the discovery of new efficacious medications. To this end, we examined hippocampal transcriptional changes in rat models of disease and in humans to identify common disease signatures by using a new algorithm for signatu...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Carboni, Lucia, Marchetti, Luca, Lauria, Mario, Gass, Peter, Vollmayr, Barbara, Redfern, Amanda, Jones, Lesley, Razzoli, Maria, Malki, Karim, Begni, Veronica, Riva, Marco A., Domenici, Enrico, Caberlotto, Laura, Mathé, Aleksander A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6098161/
https://ncbi.nlm.nih.gov/pubmed/29950584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0117-6
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