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Multicilin and activated E2f4 induce multiciliated cell differentiation in primary fibroblasts

Multiciliated cells (MCCs) are specialized epithelial cells that project hundreds of motile cilia. To form these cilia, MCCs differentiate by dramatically expanding centriole number, using assembly factors required for centriole duplication during the cell cycle and multiple, novel assembly sites, c...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kim, Seongjae, Ma, Lina, Shokhirev, Maxim N., Quigley, Ian, Kintner, Chris
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6098136/
https://ncbi.nlm.nih.gov/pubmed/30120325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30791-1
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