The effects of ketamine on prefrontal glutamate neurotransmission in healthy and depressed subjects

The ability of ketamine administration to activate prefrontal glutamate neurotransmission is thought to be a key mechanism contributing to its transient psychotomimetic effects and its delayed and sustained antidepressant effects. Rodent studies employing carbon-13 magnetic resonance spectroscopy ((...

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Pubblicato in:Neuropsychopharmacology
Autori principali: Abdallah, Chadi G., De Feyter, Henk M., Averill, Lynnette A., Jiang, Lihong, Averill, Christopher L., Chowdhury, Golam M. I., Purohit, Prerana, de Graaf, Robin A., Esterlis, Irina, Juchem, Christoph, Pittman, Brian P., Krystal, John H., Rothman, Douglas L., Sanacora, Gerard, Mason, Graeme F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6098048/
https://ncbi.nlm.nih.gov/pubmed/29977074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0136-3
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