Na/K-ATPase Y260 Phosphorylation–mediated Src Regulation in Control of Aerobic Glycolysis and Tumor Growth

We report here the identification of α1 Na/K-ATPase as a major regulator of the proto-oncogene Src kinase and the role of this regulation in control of Warburg effect and tumor growth. Specifically, we discovered Y260 in α1 Na/K-ATPase as a Src-specific phosphorylation and binding site and that Y260...

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Vydáno v:Sci Rep
Hlavní autoři: Banerjee, Moumita, Cui, Xiaoyu, Li, Zhichuan, Yu, Hui, Cai, Liquan, Jia, Xuelian, He, Daheng, Wang, Chi, Gao, Tianyan, Xie, Zijian
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6098021/
https://ncbi.nlm.nih.gov/pubmed/30120256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29995-2
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