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SUMOylation of VEGFR2 regulates its intracellular trafficking and pathological angiogenesis

Regulation of VEGFR2 represents an important mechanism for the control of angiogenesis. VEGFR2 activity can be regulated by post-translational modifications such as ubiquitination and acetylation. However, whether VEGFR2 can be regulated by SUMOylation has not been investigated. Here we show that en...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhou, Huanjiao Jenny, Xu, Zhe, Wang, Zongren, Zhang, Haifeng, Zhuang, Zhen W., Simons, Michael, Min, Wang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6098000/
https://ncbi.nlm.nih.gov/pubmed/30120232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05812-2
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