mGlu(1) and mGlu(5) modulate distinct excitatory inputs to the nucleus accumbens shell

Glutamatergic transmission in the nucleus accumbens shell (NAcSh) is a substrate for reward learning and motivation. Metabotropic glutamate (mGlu) receptors regulate NAcSh synaptic strength by inducing long-term depression (LTD). Inputs from prefrontal cortex (PFC) and medio-dorsal thalamus (MDT) dr...

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Udgivet i:Neuropsychopharmacology
Main Authors: Turner, Brandon D., Rook, Jerri M., Lindsley, Craig W., Conn, P. Jeffrey, Grueter, Brad A.
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097986/
https://ncbi.nlm.nih.gov/pubmed/29654259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0049-1
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