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Pericentromere-specific cohesin complex prevents meiotic pericentric DNA double-strand breaks and lethal crossovers
In most eukaryotes, meiotic crossovers are essential for error-free chromosome segregation but are specifically repressed near centromeres to prevent missegregation. Recognized for >85 years, the molecular mechanism of this repression has remained unknown. Meiotic chromosomes contain two distinct...
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| Publicado no: | Mol Cell |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6097939/ https://ncbi.nlm.nih.gov/pubmed/30078721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.06.035 |
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