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High chymotrypsin-like activity in the plasma of patients with newly diagnosed multiple myeloma treated with bortezomib is predictive of a better response and longer PFS

Proteasome inhibitors (PIs) such as bortezomib constitute an important part of the modern standard therapy for multiple myeloma (MM). In this study, we set out to assess whether proteasome concentration and chymotrypsin-like (ChT-L) activity could serve as potential biomarkers defining the likelihoo...

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Detalhes bibliográficos
Publicado no:Ann Hematol
Main Authors: Romaniuk, Wioletta, Bolkun, Lukasz, Kalita, Joanna, Galar, Marzenna, Bernatowicz, Malgorzata, Ostrowska, Halina, Kloczko, Janusz
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097751/
https://ncbi.nlm.nih.gov/pubmed/29946907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00277-018-3393-7
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