The use of intravenous versus subcutaneous monoclonal antibodies in the treatment of severe asthma: a review

BACKGROUND: Monoclonal antibodies (mAbs) approved for use as add-on therapy in patients with severe asthma target the underlying pathogenesis of asthma. MAIN BODY: Omalizumab binds immunoglobulin E (IgE), thereby inhibiting its interaction with the high-affinity IgE receptor and reducing the quantit...

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Bibliografiske detaljer
Udgivet i:Respir Res
Main Authors: Matucci, Andrea, Vultaggio, Alessandra, Danesi, Romano
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097430/
https://ncbi.nlm.nih.gov/pubmed/30115042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0859-z
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