Multiple Posttranscriptional Strategies To Regulate the Herpes Simplex Virus 1 vhs Endoribonuclease

The herpes simplex virus 1 (HSV-1) virion host shutoff (vhs) protein is an endoribonuclease that binds to the cellular translation initiation machinery and degrades associated mRNAs, resulting in the shutoff of host protein synthesis. Hence, its unrestrained activity is considered lethal, and it has...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Elliott, Gillian, Pheasant, Kathleen, Ebert-Keel, Katja, Stylianou, Julianna, Franklyn, Ashley, Jones, Juliet
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2018
Ämnen:
Virus-Cell Interactions
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096803/
https://ncbi.nlm.nih.gov/pubmed/29925667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00818-18
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