Kv7 channels are upregulated during striatal neuron development and promote maturation of human iPSC-derived neurons

Kv7 channels determine the resting membrane potential of neurons and regulate their excitability. Even though dysfunction of Kv7 channels has been linked to several debilitating childhood neuronal disorders, the ontogeny of the constituent genes, which encode Kv7 channels (KNCQ), and expression of t...

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Detalhes bibliográficos
Publicado no:Pflugers Arch
Main Authors: Telezhkin, Vsevolod, Straccia, Marco, Yarova, Polina, Pardo, Monica, Yung, Sun, Vinh, Ngoc-Nga, Hancock, Jane M., Barriga, Gerardo Garcia-Diaz, Brown, David A., Rosser, Anne E., Brown, Jonathan T., Canals, Josep M., Randall, Andrew D., Allen, Nicholas D., Kemp, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096767/
https://ncbi.nlm.nih.gov/pubmed/29797067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-018-2155-7
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