Low-Dose Continuous 5-Fluorouracil Combined with Leucovorin, nab-Paclitaxel, Oxaliplatin, and Bevacizumab for Patients with Advanced Pancreatic Cancer: A Retrospective Analysis

BACKGROUND: Continuous-infusion 5-fluorouracil (5FU) and calcium leucovorin plus nab-paclitaxel and oxaliplatin have been shown to be active in patients with pancreatic cancer. As a protracted low-dose infusion, 5FU is antiangiogenic, and has synergy with bevacizumab. As shown in the treatment of br...

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Detalhes bibliográficos
Publicado no:Target Oncol
Main Authors: Isacoff, William H., Reber, Howard A., Bedford, Rudolph, Hoos, William, Rahib, Lola, Upfill-Brown, Alexander, Donahue, Timothy, Hines, O. Joe
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
Assuntos:
Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096752/
https://ncbi.nlm.nih.gov/pubmed/29882102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11523-018-0572-3
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