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Approaching cellular resolution and reliable identification in mass spectrometry imaging of tryptic peptides

On-tissue digestion has become the preferred method to identify proteins in mass spectrometry (MS) imaging. In this study, we report advances in data acquisition and protein identification for MS imaging after on-tissue digestion. Tryptic peptides in a coronal mouse brain section were measured at 50...

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Detalhes bibliográficos
Publicado no:Anal Bioanal Chem
Main Authors: Huber, Katharina, Khamehgir-Silz, Pegah, Schramm, Thorsten, Gorshkov, Vladimir, Spengler, Bernhard, Römpp, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096711/
https://ncbi.nlm.nih.gov/pubmed/30066193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-018-1199-z
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