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m(6)A RNA Degradation Products Are Catabolized by an Evolutionarily Conserved N(6)-Methyl-AMP Deaminase in Plant and Mammalian Cells

N(6)-methylated adenine (m(6)A) is the most frequent posttranscriptional modification in eukaryotic mRNA. Turnover of RNA generates N(6)-methylated AMP (N(6)-mAMP), which has an unclear metabolic fate. We show that Arabidopsis thaliana and human cells require an N(6)-mAMP deaminase (ADAL, renamed MA...

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Detaylı Bibliyografya
Yayımlandı:Plant Cell
Asıl Yazarlar: Chen, Mingjia, Urs, Mounashree J., Sánchez-González, Ismael, Olayioye, Monilola A., Herde, Marco, Witte, Claus-Peter
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Plant Biologists 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096584/
https://ncbi.nlm.nih.gov/pubmed/29884623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1105/tpc.18.00236
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